Physicochemical molecular recognition.

Protein Folding Recognition Based on Amino Acid Physicochemical Property Profiles

Physicochemical Properties of the Mammalian Molecular Chaperone HSP60

The E. coli GroEL/GroES chaperonin complex acts as a folding cage by producing a bullet-like asymmetric complex, and GroEL exists as double rings regardless of the presence of adenosine triphosphate (ATP). Its mammalian chaperonin homolog, heat shock protein, HSP60, and co-chaperonin, HSP10, play an essential role in protein folding by capturing unfolded proteins in the HSP60/HSP10 complex. How...

Radically enhanced molecular recognition.

The tendency for viologen radical cations to dimerize has been harnessed to establish a recognition motif based on their ability to form extremely strong inclusion complexes with cyclobis(paraquat-p-phenylene) in its diradical dicationic redox state. This previously unreported complex involving three bipyridinium cation radicals increases the versatility of host-guest chemistry, extending its p...

Oligosaccharides in molecular recognition.

The development, organization and growth of complex organisms as well as their interactions with the environment involve an intricate array of molecular recognition events. There is an increased awareness of the involvement of oligosaccharides in many of these processes. In this article, studies of oligosaccharide antigenicity, and the way these have been interpreted with respect to oligosaccha...

Molecular Recognition of Glycopolymer Interface

Saccharides on the cell surfaces play important roles in the living systems. For example, it mediate the cell-cell adhesion, fertilization, protein transportation, infection of pathogens and cancer metastasis etc [1, 2]. The saccharide-protein interactions also involve the various biological events (Table 1). Actualy, the saccharides are the model compounds of some of the medicines like oseltam...